"Wasn't 42 the answer to life, the universe, and everything in The Hitchhiker's Guide to the Galaxy? And H2G2 is an abbreviation given to the book, as well as the name of a website dedicated to making a guide to life, the universe, and everything."
If you check YouTube.com's source code, you'll find some references to "hitchhiker".
One of YouTube's sprites has "hitchhiker" in the filename.