The Web browser becomes the primary application interface through which the user views content, performs services, and manages data on their local machine and on the Web, often without even knowing the difference. (...)
Aside from the browser and the Web server, applications will be written for the WebOS and won't be specific to Windows, OS X, or Linux. This is also completely feasible, I think, for organizations like Google, Yahoo, Apple, Microsoft, or the Mozilla Foundation to make happen.
Compared to "standalone" Web apps and desktop apps, applications developed for this hypothetical platform have some powerful advantages. Because they run in a Web browser, these applications are cross platform (assuming that whoever develops such a system develops the local Web server part of it for Windows, OS X, Linux, your mobile phone, etc.), just like Web apps such as Gmail, Basecamp, and Salesforce.com. You don't need to be on a specific machine with a specific OS...you just need a browser + local Web server to access your favorite data and apps.
More: http://www.kottke.org/05/08/googleos-webos.
